Université de Bordeaux
 

Timetable & learning outcomes

The program will integrate, similarly to the summer school organized in 2019, mixed activities with theoretical courses, practical sessions, applied lectures, videos and round table sessions.

Course content will be divided into lectures on methods and instrumentation (incl. latest generation instrumentation and methods) and lectures and applied interactive sessions on case studies (incl. works of art, museum objects and archaeological / palaeontological samples). Practical sessions will include sample preparation; analysis of peptide, lipid and saccharide fingerprints; bottom up / top down proteomics of ancient proteins; screening and quantification of lipids; mass spectrometry imaging; data processing (sequencing, biological origins, etc.); structural analysis of ancient macromolecules (proteins, lipids, sugars), etc. Particular attention will be paid to the current questions of cultural heritage stakeholders and to the challenges ahead.

Tentative program

Wednesday June 16th, 2021

 

08:00 

08:30

Virtual registration

 
 

08:30

09:00

Opening remarks

 
 

09:00

09:45

Opening lecture - Mass spectrometry applied to cultural heritage: current achievements and future challenges

Caroline Tokarski 

 

09:45

10:30

Lecture - Sample preparation and minimally invasive methods for proteomics: principles and case studies applied to artworks and archaeological samples

Leila Birolo

 

10:30

10:45

Break

 
 

10:45

12:45

Group 1:

  • Practical session - LC MS Methods: from bottom up to top down proteomics - Part 1 Instrumentation and methods

Group 2:

  • Practical session - MALDI-based methods: PMF, sugars fingerprints, proteins, lipids

Francesca Galluzzi, Stéphane Claverol, Jean-William Dupuy

Katell Bathany, Stéphane Chaignepain

 

12:45

13:30

Lunch

 
 

13:30

16:45 

Advanced mass spectrometry and analysis in museums

Lecture - Chemistry and art at the Metropolitan Museum of Art [New York]: natural organic polymer investigations

and

Lecture - Analysis at the National Museum of Prehistory [Les Eyzies] and international principles of resource preservation and knowledge development in archaeology


and

Lecture - Ambient sampling and ionization for mass spectrometry of museum objects and materials

and

Lecture - Lipid degradations in heritage material [Rijksmuseum, Amsterdam]

Julie Arslanoglu

and 

Nathalie Fourment

and

G. Asher Newsome 

and

Katrien Keune

 

16:45

17:15

Discussion - Advanced mass spectrometry and analysis in museums

Aleksandra Popowich

 

17:15

17:45

Virtual cocktail and attendee presentations

 
 

17:45

18:45

Virtual icebreaker

 

Thursday June 17th, 2021

 

08:00

08:30

Virtual breakfast

 
 

08:30

09:15

Lecture - Palaeoproteomics to unleash the study of human history

Enrico Cappellini

 

09:15

10:00 

Lecture - Bioinformatics of ancient proteins

Juergen Cox 

 

10:00

10:15 

Break

 
 

10:15

12:15

Group 1:

  • Practical session - LC MS Methods: from bottom up to top down proteomics - Part 2 Data processing

Group 2:

  • Practical session - Lipid analysis: LC-MS, MRM

Francesca Galluzzi, Stéphane Claverol, Jean-William Dupuy

Corinne Buré, Caroline Le Senéchal

 

12:15 

13:00

Lunch

 
 

13:00

14:15

Lecture - Part 1 - Zoom MS: past, present, future

Lecture - Part 2 - Authentication of ancient proteins

 Matthew Collins 

 

14:15

16:15

Group 1:

  • Practical session - MALDI-based methods: PMF, sugars fingerprints, proteins, lipids

Group 2:

  • Practical session - LC MS Methods: from bottom up to top down proteomics - Part 1 Instrumentation and methods

Katell Bathany, Stéphane Chaignepain

Francesca Galluzzi, Stéphane Claverol, Jean-William Dupuy

 

16:15

16:30 

Break

 
 

16:30 

17:15 

Lecture - Archaeometry, mass spectrometry and 3D technologies: how can they match?

 Rémy Chapoulie

 

17:15

18:30

Virtual escape game

 

Friday June 18th, 2021

 

08:00

08:15

Virtual breakfast

 
 

08:15

09:30

Lecture - Part 1 - MS imaging fundamentals and MSI applied to cultural heritage

Lecture - Part 2 - SAWN MS applied to heritage

Garry Corthals

 

09:30

11:15

Groups 1 & 2:

  • Practical session - MS imaging

Nicolas Desbenoit, Landry Blanc, Michael Tuck

 

11:15

11:30

Break

 
 

11:30 

13:30 

Group 1:

  • Practical session - Lipid analysis: LC-MS, MRM

Group 2:

  • Practical session - LC MS Methods: from bottom up to top down proteomics - Part 2 Data processing

Corinne Buré, Caroline Le Senéchal

Francesca Galluzzi, Stéphane Claverol, Jean-William Dupuy

 

13:30 

14:15

Lunch

 
 

14:15

15:00 

Lecture - GC-MS and PyGC-MS applied to the study of organic material – proteins, lipids, polysaccharides - in artworks and archaeological samples

Ilaria Bonaduce

 

15:00

15:45 

Closing lecture - Ethics: research and practice

Sven Haakanson

 

 15:45

16:45

Round table - Contribution of modern mass spectrometry to major questions of cultural heritage

Francesco d’Errico, Julie Arslanoglu, Matthew Collins, Sven Haakanson

 

16:45

17:00

Break

 
 

17:00

17:45

Attendee lightning round

 
 

17:45

18:15

Concluding remarks

 

 

Expertise upon completion

The summer school offers a unique opportunity to develop strong knowledge in advanced mass spectrometry within a program which links analytical chemists, physicists, experts in formulation, computational modeling experts, conservators, restorers and archaeologists.

A certificate of participation will be awarded to students upon completion of the course.

Program may be subject to change. 



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